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The UMB Postdoctoral Network
 
 
 









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Laurel S. Burall
Graduate of University of Maryland, Baltimore, 2004

LBurall@umaryland.edu

Mentor: Dr. Patrik Bavoil
Deptartment of Biomedical Sciences

Research

My research focuses on using genomics to study Chlamydia.  This work has led to the characterization of ilp as an expressed gene without an associated phenotype or protein.  My current research is a comparative genomic analysis of two wildtype C. abortus strains and a vaccine strain to identify the mechanism of attenuation.

Research Techniques

Genomics, RT-PCR, Immunoblot Analysis

Personal History

As an undergrad, I attended St. Mary's College of Maryland, where I received my B.A. in Biology in 1998.  I then came to the University of Maryland and received my Ph.D. in Microbiology & Immunology in 2004.  I have since been a postdoctoral fellow in the laboratory of Patrik Bavoil.

Publications

Journals:
  • Liu, Z., R. Rank, B. Kaltenboeck, S. Magnino, D. Dean, L. Burall, R.D. Plaut, T.D. Read, G. Myers, and P.M. Bavoil.  Genomic Plasticity of the rrn-nqrF Intergenic Segment in the Chlamydiaceae.  J. Bacteriol. In press.
  • Burall, L.S., J.M. Harro, X. Li, C.V. Lockatell, S.D. Himpsl, J.R. Hebel, D.E. Johnson, H.L. Mobley.  (2004)  Proteus mirabilis Genes That Contribute to Pathogenesis of Urinary Tract Infection: Identification of 25 Signature-Tagged Mutants Attenuated at Least 100-fold.  Infect. Immun. 72, 2922-2938.
  • Guedez, L., L. Courtemanch, M. Stetler-Stevenson.  (1998)  Tissue Inhibitor of Metalloproteinase (TIMP)-1 Induces Differentiation and an Antiapoptotic Phenotype in Germinal Center B Cells.  Blood. 92, 1342-1349.
Abstracts:
 
  • Burall, L., A. Rekiki, A. Rodolakis, and P.M. Bavoil.  Comparative Analysis of Wild-type and Attenuated C. abortus Genomes.  Chlamydia Basic Research Society.  Memphis, TN March 2007.
  • Burall, L., A. Rekiki, and P.M. Bavoil.  Comparative Analysis of the Genome Sequences of C. abortus S26/3 and AB7.  American Society for Microbiology Orlando, FL General Meeting May 21-25, 2006.
  • Burall, L., A. Rekiki, A. Rodolakis, and P.M. Bavoil.  Analysis of C. abortus Genomes and Their Role in Pathogenicity.  4th Workshop of the European Cooperation in the field of Scientific and Technical Research (COST) Action 855 on Zoonotic Aspects of Animal Chlamydioses. Edinburgh, UK Sept. 3-5, 2006.
  • Burall, L., Z. Liu, and P. Bavoil.  Studies of a Chlamydial Invasin-like Protein.  American Society for Microbiology.  Atlanta, GA General Meeting June 5-9, 2005.
  • Burall, L.  and H. Mobley.  HdfR Regulation of Swarming and Swimming Motility in Proteus mirabilis.  American Society for Microbiology. New Orleans, LA General Meeting May 23-27, 2004.
  • Burall, L., R. Hebel, D. Johnson, C. Lockatell, and H. Mobley.  Identification and Characterization of Iron Acquisition Systems Required for Virulence of Uropathogenic Proteus mirabilis.  American Society for Microbiology Washington, DC General Meeting May 18-22, 2003.
  • Burall, L., R. Hebel, D. Johnson, C. Lockatell, and H. Mobley.  Novel Virulence Factors of Proteus mirabilis Involved in Swarming and Iron Acquisition Identified by Signature-Tagged Mutagenesis.  American Society for Microbiology.  Salt Lake City, UT May 19-23, 2002
  • Courtemanch, L., C.A. May, H.L.T. Mobley, and J.L. Slonczewski.  Urease Regulation in Proteus mirabilis: pH Dependence and Putative Domains of UreR.  American Society for Microbiology Chicago, IL. General Meeting May 30- June 3, 1999.

 

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