Directory

Jan Peters
Graduate of University of Hanover, Germany, 2004

Mentor: Dr. Patrik Bavoil
Department of Biomedical Sciences, Dental School

Research

My research focuses on the Type III Secretion System of the obligate-intracellular bacterium Chlamydia, which allows the direct translocation of effector proteins into the cytosol of target eukaryotic cells. My current research has led to the development of a fluorescence based beta-lactamase system to identify chlamydial effector proteins. Further studies will involve the identification of potential eukaryotic binding partners of chlamydial effectors.

Research Techniques

Personal History

I studied Biochemistry at the University of Hanover, Germany from 1996 to 2001. The studium included a Prediploma degree in Biochemistry (1998) (Bachelors degree equivalent) and ended in 2001 with a Diploma in Biochemistry, Biophysical Chemistry, and Medical Microbiology (Masters degree equivalent). I received my Ph.D. in Biochemistry and Microbiology at the University of Hanover in 2004. I have been employed as a postdoctoral fellow in the Bavoil lab at the University of Maryland Baltimore since January 2005.

Publications

Journals:

Peters J, Hess S, Endlich K, Thalmann J, Holzberg D, Kracht M, Schaefer M, Bartling G, Klos A.: Silencing or Permanent Activation: Host-cell Responses in Models of Persistent Chlamydia pneumoniae Infection. Cell Microbiol. 2005 Aug; 7(8):1099-108.
Hess S, Peters J, Bartling G, Rheinheimer C, Hegde P, Magid-Slav M, Tal-Singer R, Klos A.: More Than Just Innate Immunity: Comparative Analysis of C. pneumoniae and C. trachomatis Effects on Host-Cell Gene Regulation. Cell Microbiol. 2003 Nov; 5(11):785-95.

Abstracts:

Peters J. and Bavoil P.M.: The Late Type III Secreted Effector Protein CopN Targets a Key Enzyme of the Host Glycolytic Pathway, Chlamydia Basic Research Society Louisville, KY March 2007
Peters J. and Bavoil, P.M.: A Fluorescence-Based Beta-Lactamase Fusion System for the Identification of Chlamydial Type III Secretion Effector Proteins: Chlamydia Basic Research Society, Louisville, KY March 2007
Peters J., Tatsuno I., Kaper J., and Bavoil P.M.: Establishment of a Fluorescence-Based Beta-Lactamase System for the Identification of Chlamydial Type III Secretion Effector Proteins; American Society for Microbiology Orlando, FL General Meeting May 2006
Peters J. Hess S., Endlich K., Bartling G. Klos, A.: Hide-and-Seek: Host-Cell Responses in Models of Persistent C. Pneumoniae Infection; 2. German Chlamydia Workshop, Berlin, Germany, March 2004
Peters, J., Hess, S., Endlich, K., Bartling, G., Klos, A.: Hide-And-Seek: Host-Cell Responses in Models of Persistent Chlamydophila Pneumoniae Infection; 5. Meeting of The European Society for Chlamydia Research, Budapest, Hungary, September 2004
Peters, J., Hess, S., Endlich, K., Bartling, G., Klos, A.: Hide-And-Seek: Host-Cell Responses in Models of Persistent Chlamydophila Pneumoniae Infection; 56. Conference of The German Society for Hygiene and Microbiology, Muenster, Germany, September 2004
Hess, S. Peters, J., Rheinheimer, C., Bartling, G., Dietrich-Kruppa, C., Hedge P., Magid-Slav M., Tal-Singer R., Klos, A.: Comparative Analysis of C. pneumoniae and C. trachomatis Effects on Host Cell Transcriptome; 1. German Chlamydia Workshop, Berlin, Germany, February 2003
Endlich K. Peters J., Hess S., Bartling G., Klos A.: Host-cell Responses in Models of Persistent C. Pneumoniae Infection; 55. Conference of The German Society for Hygiene and Microbiology Dresden, Germany, September 2003
Hess, S. Peters, J., Rheinheimer, C., Bartling, G., Dietrich-Kruppa, C., Hedge P., Magid-Slav M., Tal-Singer R., Klos, A.: Comparative Analysis of C. pneumoniae and C. trachomatis Effects on Host Cell Transcriptome; 54. Conference of The German Society for Hygiene and Microbiology, Heidelberg, Germany, October 2002

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