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The UMB Postdoctoral Network
 
 
 









Joseph Antonio Roche
Graduate of University of Maryland Baltimore, 2008

jroche@som.umaryland.edu

Mentor: Dr. Robert J. Bloch
Physiology


Research

Schematic of dysferlin at the sarcolemma

Research Techniques

Skeletal muscle electrophysiology
Whole animal physiology
Fluorescence microscopy
Protein assays
Gene expression assays

Personal History

Personal Information
• Business address:  685 West Baltimore Street.  HSF-1 Room 580.
 Department of Physiology, University of Maryland Baltimore 
 Baltimore, MD 21201.
• Business Phone Number.  410-706-2665, 443-413-9494 (cell). 
• Fax Number.  410-706-8341.
• Email.  jroche@som.umaryland.edu

Publications

Abstracts
• A mouse model of eccentric contraction-induced skeletal muscle injury.  Roche JA, Lovering RM, and Bloch RJ.  Graduate Research Conference.  Baltimore, MD.  USA.  April 2004.          
• The contribution of sarcolemmal  repair to recovery after an acute skeletal muscle strain.  Roche JA, Lovering RM, Bloch RJ, De Deyne PG. Paper Number: 1875. 52nd annual Meeting of the Orthopedic Research Society.  Chicago,IL.  USA. March 2006.
• Differences in myogenesis and sarcolemmal repair after single and repetitive muscle strains.  Lovering RM, Roche JA, Bloch RJ, De Deyne PG.  New Directions in Biology & Disease of Skeletal Muscle.  Dallas, TX.  USA.  April 2006.     
• The contribution of sarcolemmal repair and myogenesis to recovery after skeletal muscle injury.  Roche JA, Lovering RM, Bloch RJ, De Deyne PG Baltimore, MD.  USA.  Graduate Research Conference.  Baltimore, MD.  USA.  April 2006. 
• Delayed Recovery of Skeletal Muscle Function in Dysferlin-deficient Mice following Large-strain Lengthening Contractions. Roche JA, Lovering RM, Bloch RJ.  Podium presentation.  Graduate Research Conference.  Baltimore, MD.  USA.  April 2007.     
• Delayed Recovery of Skeletal Muscle Function In Dysferlin-deficient Mice Following Large-strain Lengthening Contractions.  Roche JA, Lovering RM, Bloch RJ.  Annual Meeting of the American College of Sports Medicine.  New Orleans, LA.  USA.  June 2007.
• The Giant Sarcomeric Protein Obscurin as a Potential Regulator of RhoA Signaling in Skeletal Muscle.  Ford DL, Roche JA, and Bloch RJ.  Joint Annual Meeting of the Biophysical Society and the International Biophysics Congress.  Long Beach, CA.  USA.  February 2008.           
• Muscle physiology, membrane structure, and susceptibility to injury in animals lacking keratin 19 and/or desmin.  Lovering RM, O'Neill A, Muriel JM, Roche JA, Prosser BL, and Bloch, RJ.  New Directions in Biology & Disease of Skeletal Muscle.  New Orleans, LA.  USA.  April-May 2008.
   
Manuscripts
• Impaired recovery of dysferlin-null skeletal muscle after contraction-induced injury in vivo. Roche JA, Lovering RM, Bloch RJ. Neuroreport. 2008 Oct 29;19(16):1579-84.
• Phospholipid-Induced In Vivo Particle Migration to Enhance Pulmonary Deposition.  Ganguly S, Moolchandani V, Roche JA, Shapiro PS, Somaraju S, Eddington ND, Dalby RN. J Aerosol Med Pulm Drug Deliv. 2008 Sep 29. [Epub ahead of print].
• Identification of skeletal muscle mutations in tail snips from neonatal mice using immunohistochemistry.  Lovering RM, O'Neill A, Roche JA, Bloch RJ.  Biotechniques. 2007 Jun;42(6):702, 704.
• Recovery of function in skeletal muscle following 2 different contraction-induced injuries.  Lovering RM, Roche JA, Bloch RJ, De Deyne PG.  Arch Phys Med Rehabil. 2007 May;88(5):617-25.

 

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